Drug Name | Brand Name | Indications | Drug Class | Mechanism of Action |
Montelukast sodium | Singulair | Asthma; Asthma prophylaxis | Leukotriene Pathway Inhibitor | An active leukotriene receptor antagonist that binds to cysteinyl leukotriene type-1 receptors (found in airway smooth muscle cells and macrophages) and prevents airway edema, smooth muscle contraction, and inflammation. |
Zafirlukast | Accolate | Asthma | Anti-inflammatory; Leukotriene Pathway Inhibitor | Selective and competative cysteinyl leukotriene D4 and E4 receptor antagonist. It also reduces bronchial hyper-responsiveness to inhaled histamine and other allergens. |