Drug Name Brand Name Indications Drug Class Mechanism of Action
Montelukast sodium Singulair Asthma; Asthma prophylaxis Leukotriene Pathway Inhibitor An active leukotriene receptor antagonist that binds to cysteinyl leukotriene type-1 receptors (found in airway smooth muscle cells and macrophages) and prevents airway edema, smooth muscle contraction, and inflammation.
Zafirlukast Accolate Asthma Anti-inflammatory; Leukotriene Pathway Inhibitor Selective and competative cysteinyl leukotriene D4 and E4 receptor antagonist. It also reduces bronchial hyper-responsiveness to inhaled histamine and other allergens.